Job Description

Job Description

Principal Investigator – Clinical Research

Hours: Full-time, Monday–Friday, 8:00 AM – 2:30/4:30 PM

Salary: $250,000 – $300,000 base + full benefits package

Company: Metric Search, partnered with a leading Clinical Research Organisation

About the Role

Metric Search is proud to partner with a leading, multi-site Clinical Research Organisation operating across a network of 18 clinical research sites. We are seeking a Principal Investigator to join one of their established research centres, contributing to industry-leading clinical trials and advancing medical innovation.

This is a full-time, on-site role with prior experience serving as a Principal Investigator (or extensive Sub-Investigator experience).

Key Responsibilities

• Serve as the Principal Investigator for assigned clinical trials, ensuring all studies are conducted in accordance with ICH-GCP and regulatory requirements.
• Collaborate with study sponsors and CRO teams - acting as the site’s subject matter expert (SME) in your field.
• Provide medical oversight for study participants, including in-house or virtual patient calls during business hours.
• Rotate after-hours call duties with two other investigators (no after-hours phone coverage required individually).
• Participate in investigator meetings, sponsor calls, and industry conferences.
• Support site operations and patient recruitment during both high- and low-enrolment seasons.

Ideal Candidate

• Board-certified.
• US Medical License.
• Experience as a Principal Investigator preferred; Sub-Investigator experience in Pfizer-sponsored or major pharmaceutical trials will be strongly considered.
• Committed to full-time site involvement (no multiple practice commitments).
• Passionate about clinical research and patient-centred science.
• Strong communicator with a collaborative, leadership-oriented approach.

What’s on Offer

• Competitive base salary of $250,000 – $300,000
• Relocation support provided
• Opportunity to work within a network of 18 sites
• Regular exposure to sponsors, industry leaders, and conferences

If this sounds like your next step, please apply, or contact executive search consultant - Oli Oldham on oli.oldham@metric-search.com.

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